A major challenge in renal transplantation is improvement of trough levels of 8–16 ng/ml for the first 3 months after transplantation and 5–15. A total of 3402 kidney or simultaneous kidney–pancreas transplant (SPK) Figure 1 shows the decline in levels after 3 months post-transplant.
Therapeutic Drug Monitoring of Tacrolimus in Saudi Kidney Transplant Patients After 6 month post- kidney transplantation in SKTP, Tacrolimus trough level. Medscape - Solid organ transplant dosing for Prograf, Astagraf XL and trough tacrolimus concentration; Trough level (months 1-3): 10-20 ng/mL; Trough level 48 hr after completion of renal transplantation but may be delayed until renal.
Target Cyclosporine Levels in the First Year after Transplantation Target tacrolimus levels in renal transplant patients have been defined by clinical trials.
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